I am 42 and after 1 failed IUI and 1 failed IVF, I am now starting my second round IVF with the lupron flare and ICSI. BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. They said my FSH and AMH levels were really good too so i just think i'm a poor responder to IVF in general! fainting. Read Review Toronto Licence Claim Delta. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. For those women whove had more than one ivf cycle, did you change protocol? So it seems to me it's time to change the protocol, do another cycle and gather more inform, HelloHave been reading the boards, but have never posted. I am priming now with only growth hormone and will start my cycle next week. Each month is different and that 4 eggs could have been just an off month and not a predictor of your future cycles. And where there is variation? Lap 2/15. High FSH. I stimmed for 12 days and only ended up with two mature eggs. I think it helps with the 2ww. --- EDD 4/5/15, "Everything will be alright in the end. GL! . 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. You and your husband will start your Doxycycline antibiotics today. My little one is a success story from MDL! I am curious why your RE thinks this is the right protocol for you - obviously he/she has all the facts on ya! My first and second retrievals were from an antagonist protocol which gave us 4 PGS normal embryos for the first cycle and 2 embryos (untested) the next cycle. On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . It worked for me! Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 Long-term Storage for Eggs, Sperm & Embryos. 0000001853 00000 n The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. [Sheri] What is DHEA? My FSH is 6.5. My first retrieval was an antagonist protocol, and we only got one poor quality embryo (3CB). For those of you unfamiliar, mini stim is for poor responders who don't have much luck in obtaining a large number of eggs. I wrote a post yesterday before I even read up on this type of protocol. Thanks! I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. [curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. Instead I'll have my blood checked for progesterone levels to see where I am in my cycle (since the cancelled IVF fucked that all up). With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . Microdose Lupron Flare Protocol. An EPP for you. Round Three Result 6/25: BFN Infertility Support Community in Partnership with RESOLVE. Beta1 9/10: 152.7! If so, I'd love to hear thoughts/experiences. 11 mature. Thank you so much for joining along on this. Maybe he will change with time but for.now, we are pursuing myeggs actively. EDD 5/11/14, Jack dx at 19w1d with Dandy Walker on 12/16/13, Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13, FET #2 --July 2014 BFP! This is the last round of treatment we'll be able to afford and I'm starting to get a lot of anxiety since stims are starting next weekend. Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. I'm the poster child for lupron flair. My doctor refunded some costs and wants me to try again. We feel so much more comfortable with him because he is all about the science, and none of the bullshit. Following. Women with high LH or FSH levels, decreased ovarian/egg reserve and a history of prior poor response to ovarian stimulation benefit the most from such a protocol. I am also doing acupuncture for 3 months. I just finished day 4 of gonal, microdose and letrozole. It is similar to IVF with the injectable, Hello -- I've found myself in a really sad, desperate place, and so I'm posting to get any insight on my current protocol/choices. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. However, I think I am in the minority as clearly it works incredibly well for some. I did microdose lupron flare protocol with my first IVF. Thin Lining - stim protocol - suggestions? Get weekly updates on baby and your body. Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. I am not familiar with it, but I will definitely some research. 5DT. Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. IVF3 (ICSI/CCS): Antagonist with EPP What's weird is all of my levels are normal and i'm so young so i think the doctor and nurses are all perplexed as to how my egg quality was so bad! In order to retrieve the eggs before they ovulate spontaneously, the patient is taken into the operating room and the eggs are removed non-surgically approximately 36 hours following hCG administration. I am hoping and praying that all 4 make it to day 5 for. Note that once you confirm, this action cannot be undone. 0000001169 00000 n The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Er 1: 5 mature eggs, follistim 200 iu everyday with ganirelix, no menopur, no priming - frozen. Wehave3 CCS Normal Embryos! Can someone explain to me the difference in the protocols? While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. Thanks in advance! Your diagnosis of I had 6 unexplained failure FETs. I am feeling dejected, as I have had 3 cycles in the last 6 months, in which I have ovulated early twice. 1st ultrasound 10/1: TWO beautiful heartbeats! Then my friend hadsuccess with Micro dose lupron flareprotocol so I asked my dr to put me on the exact same one. 28 years old, first IVF cycle cancelled?! Thank you! When I talked with ccrm on the phone, it sounds like I'll be doing EPP with my next cycle (also #4 for me!).. Fraternal girls born Dec 2010 2011 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP . BFN My first two cycles yielded one lousy frozen each. 2005-2023Everyday Health, Inc., a Ziff Davis company. It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. Right now, they are doing an antagonistic approach. Er 6- jan 2021- GH and estrace priming for 4 days. Any help would be greatly appreciated looking for hope this time around.. Hi everyone, does anyone have any thoughts on which protocol is better for older women and which protocol is best for retrieving good quality, chromosomally normal eggs? 2TFR'ed. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. 2nd U/S @ 7w2d. 1 10cell Grade 4, 1 8cell Grade 4. Create an account or log in to participate. 39 year old multiple failed cycles need advice. Long time reader, first time poster. Microdose Lupron Flare Protocol In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. We then changed to a flair protocol for our third (I believe we used cetrotide in place of lupron but that might be regional difference). Stimulation Day 1 You will start gonadotropin injections today. Thanks!! So it seems to me it's time to change the protocol, do another cycle and gather more inform. It seems to be . We use during the pill from person through luteal phase. Lupron Trigger During Stimulated IVF Cycles. V-dot patches(20)=estrogen Where do we go from here? skin rash, hives, or itching. I do believe the MIcrodose Flare P is the way to go for women older with fewer eggs. I have a quick question for the veterans. April '14 Planning IVF attempt #3. HOORAY. They are concerned about egg quality. Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. EPP with CCRM has been my best cycle yet in regards to embryo quantity and quality! We learned, after mont, Hello 0000009011 00000 n Hello! Learn more about, Twins & Multiples: Your Tentative Time Table. Round One Result: Chemical Pregnancy Hi has anyone done a MENOPUR only cycle? Thoughts on different protocols? [Dr. William Schoolcraft] Lee, either micro dose Lupron flare or a new protocol utilizing estrogen priming steroids and antagonists. Does any have any experience or feedback with this treatment plan?? Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). Progesterone supplementation starts 2 days after the egg retrieval regardless of whether the embryo transfer occurs on Day 3 or Day 5 after retrieval and continues until the time of the pregnancy test. Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. It is quality that matters. I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. Switch Protocol 2nd Time Around? Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). We aimed to compare cost effectiveness between these two cycle types in women . does your doctor use a medication called "orlissa" ? Two different clinics. 1Frostie. Hi, Corpus Christi, TX 78413. Estrogen primed microdose lupron flare protocol karela After 5-6 days of stimulation an antagonist is added to prevent ovulation until the day of. 16 0 obj<> endobj Short Lupron (Microdose or Flare) Protocol for IVF. My AFC was 7 on day 3. Any success stories ? I did estrogen priming, microdose lupron, letrozole, menopur, and gonal f and had my best cycle ever. Your nurse will phone you with instructions by 5:00PM this day. I did my first IVF at 39 got 3 embryos with one pgta normal. In this regimen, a patient will take BCPs for 3-4 weeks. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to support the lining. How long did you wait for next cycle? Only recently. What was your protocol before? Five days before her last BCP, she will start Lupron. You start today right?!? Press J to jump to the feed. New Braunfels, TX 78130, 18707 Hardy Oak Blvd, Ste. But other doctors have mentioned that it is great for women with DOR. I don't fit into either of those categories, but I am excited to try a different protocol. In patients with low egg reserve, this combination may exert too much suppression on the ovaries. On day 6 of cycle I had three 6 mm follicles, low estrogen and cycle was cancelled. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . The other thing is they tell me that with microdose your retrieval is later. Best of luck! I did microdose lupron flare protocol with estrogen priming for 3 IVF cycles. This handout is staff as legal aid cannot provide patients with general information. Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . Results were 13 eggs retrieved, 6 mature, 2 fertilized, 2 transferred Day 3, and 1 baby boy. Use of this site is subject to our terms of use and privacy policy. For my IVF cycle I was on bcps for two weeks. First time posting here. An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. Wowzers!!! Both my l, Short protocol or long protocol for older women. IVF protocol. I did this protocol for my cycle. Countless BFN(s) Thanks for all your responses! October '13 Started BCP for December IVF. Your stories have all made me feel better. trailer In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. I am 28. Has anyone done this Lupron STOP protocol? I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. I also turned 39 this week so alsonfeeling dejected why I cant make normal embryos. Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. So Im not sure how that changes for you, since you were able to get eggs. So i'm hoping in the downtown I can get my eggs up to good quality! IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. Hi ladies,My RE proposed for my IVF#5 the micro flare protocol with BCP priming. If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. So- that's what's going on. Advanced Fertility Care Injection Teaching Videos. Are you sure you want to block this member? It's so hard to imagine that something might work when everything else hasn't. I am going in for my 4th IUI in what was supposed to be an IVF cycle. You're on your 4th so you should have a lot of good info guiding your RE in this direction For me, I did 3 IUIs with 6 follies initially, then 4, then only 2, respectively, and on IVF#1 I had only 2 follies so we canceled and just did IUI, all of this BFN, and IVF#2 only had ONE follie which we did the ER w/ICSI and it didn't fertilize. Although the fertilization and clinical pregnancy rates were not different in the groups, the implantation rate was significantly higher in the microdose flare-up group than in the multiple-dose antagonist group (22% vs. 11%). My blog about IF and loss [CLC] Can the use of Femara for 5 days with stimulants hurt the egg quality? BFP on FRER 5dp5dt: IN SHOCK! I think it was high though, like that. Infertility Support Community in Partnership with RESOLVE. They did also have me on growth hormone and 2 of the eggs they matured in the lab and my husband gave more semen & those developed into embryos. I havent heard good things and Im dreading it, worried its going to make me crazy and feel sick. 11 retrieved, 10 matured and fertilized and 4 blasts and 1 normal. They have me on Follistim, Low Dose HCG, and Ganirellex. Foll, and Meno. Are you sure you want to block this member? Microdose lupron/micro flare lupron vs agonist-antagonist ivf protocol. They are giving three more days on stimming before making the call. Please specify a reason for deleting this reply from the community. MENTS: This time around I did estrogen priming and the results of my day 5 ultrasound were disappointing (8 follicles, with an E2 level of 98.6) and now at day 7 they are worse (2 of the smaller follicles haven't budged in size so only 6 seem to be in the game but 3 are leading). I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. April '14 Planning IVF attempt #3. I also estrogen primed for this one - so it was a slow and steady stimming process, but I am not unhappy about the yield. Age: me - just turned 37 / husband 42 0000001040 00000 n 3 were mature, and only one fertilized. My first stim cycle was Antagonist and we actually did cancel ER. 2TFR'ed. Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! I did estrogen priming with no BCP for this cycle (in addition to several other changes). Im in LA but able to travel anywhere. -High School Sweethearts, about to celebrate our 18th year together. How to Cope After a Failed IVF Cycle Cry and Sob and Wail. Two fertilized and on Sunday I find out how many I am carrying. thanks ! And any other recommendations on clinics? And I wasnt pregnant. This endogenous or internal FSH acts directly on the patients ovaries and it is then reinforced with very high doses of exogenous (injections) FSH to cause the ovaries to respond as well as they possibly can. This seems really high to me. Now.our concern is premature ovulation and he is monitoring me more for that. Lupron flare was a winner for me, for sure. After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. Non left to freeze --> BFN IVF#5 (April/May 2014): Antagonist Estrogen Priming -Cornell Protocol (Clomid+ Menopur+Gonal F + Orgalutran) And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." Long awaited FET on 9/3. I am currently priming with growth hormone waiting for my period. xref Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. Our IVF #1 was cancelled in March due to low response to stims. BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). Texas Fertility Center has brought world-class care to San Antonio, Austin, Round Rock, Central Texas, and the entire Southwestern United States. :), I'm confused by all the information out there for women over 40. MII oocytes with the microdose flare group. I would like to know if any has been on the EPP/ MDL protocol ? I'm wondering if, Looking for thoughts from IVF veterans on what you did if you had a cancelled cycle. Afte, Hi all, Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). My little one is a success story from MDL! 0000002680 00000 n I'm almost 36 and have been TTC for 2.5 years. When I stimmed, this is also the thickest I ever was. Your post will be hidden and deleted by moderators. Total noob question about protocols - don't be offended. Concerns about timing of Lupron Depot protocol, Insight on New FET Protocol? If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Not attempted transferring anything yet. Apparently we waited too long ? 0000002254 00000 n Doc consult at the end of this month. 1) focus on the quality (not quantity) of eggs. I was put on Lovenox- everyday injection- and I am 26 weeks pregnancy tomorrow. This is my second attempt at ivf my first ivf was unsuccessful no embryos made it to day 5. Instead, we've had two "highly unusual" experiences and I could really use some input. Meanwhile, we're running out of solutions. I feel like it's always better to go slow & steady. The sad part of the story is that my dr was so excited and confident I would get pregnant he transfered In all 3 fresh cycle. <<7e73b458605e884a9eec5f5e9aeedda8>]>> The patient is given twice-weekly injections of estradiol valerate (Delestrogen) for a period of 8 days whereupon COS is initiated using a relatively high dosage FSH- (Follistim, Fostimon, Puregon or Gonal F), which is continued along with daily administration of GnRH antagonist until the "hCG "trigger." But after the estrogen my 3 follilces seemed to be more closely matched in size. Has anybody over 38-40 with DOR tried lupron flare and had success? I had 16 eggs, 10 mature and all 10 fertilized. I'm nervous that round 2 will go the same way as round 1. This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. I never imagined having to get to #4, but I know none of us do. EPP Antagonist was not a good protocol for me. It was my first IVF after a failed IUI. S:\Medical Forms\IVF Forms\Microflare Protocol\03-21-06 Sunday Gonadotropin Cycle Start MICRO-DOSE LUPRON FLARE PROTOCOL Sunday Monday Tuesday Wednesday Thursday Friday Saturday OCP's: Ortho Novum 1/35 (continue for 2-3 weeks) Baseline Sonogram Take Last OCP Lupron 0.2 cc 2 times each day until HCG Stimulation medication start This medicine reduces the amount of testosterone in men or estrogen in women. Previos Post Next Post Ugh, this totally blows!!!! I tell myself the poor responder is compared with someone with PCOS and not a "normal" fertile person. And can someone generally explain the 'steps' to me? 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Or tips on handling side effects? It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. So now we are dealing with issues on my side and i'm only 26 years old. I really believe that its a miracle protocol for those who are poor responders. Clomid+ 150 iu follistim+150iu menopur and GH every other day. Dont get discouraged. And Yay for no BCP, I hate that stuff, I've done all the different methods with the exception of EPP. 0000001323 00000 n I am also a poor responder but I havent tried that protocol- curious to see how it goes. My first 2 retrievals were in 2014, 2016 which were just egg freezing cycles and I cannot access them.now due to covid.
